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人微小病毒B_(19)(Human Parvovirus B_(19))可致急性再障危象、传染性红斑、关节炎、血管性紫癜及孕妇流产和死胎,作者业已用酶免疫技术及聚合酶链反应(PCR)方法证实国内存在此种病毒感染。本研究通过PCR检测小儿骨髓、血清标本中B_(19)病毒DNA,以探讨B_(19)病毒感染与小儿某些疾病的关系。
Human Parvovirus B_ (19) has been shown to cause acute aplastic anemia, infectious erythema, arthritis, purpura and miscarriage and stillbirth in pregnant women. The authors have used enzyme immunoassay and polymerase chain reaction (PCR) method to confirm the existence of such a virus infection in China. In this study, B 19 virus DNA was detected by PCR in pediatric bone marrow and serum to explore the relationship between B 19 virus infection and some diseases in children.