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目的探讨磁显葡胺增强磁共振血管成像(简称Gd-DTPA-MRA)表现及相关MRI改变对中、重度单纯疱疹病毒性脑炎(HSE)诊断价值及依达拉奉的治疗应用。方法回顾性分析53例经脑脊液常规,脑电图,颅脑CT等检查临床怀疑的中、重度HSE患者进行MRI及增强MRA检查,48例确诊,确诊患者随机分为两组,实验组应用依达拉奉配合传统抗病毒等治疗,对照组22例行传统抗病毒等治疗。结果 MRA显示全脑动脉及细小分支和静脉系统,48例单纯疱疹病毒性脑炎增强磁共振血管成像表现正常。实验组临床治疗的显效率明显高于对照组,存在差异(P<0.05)。结论临床可应用增强MRA技术对怀疑HSE的患者进行确诊,依达拉奉对治疗HSE具有明显的效果。
Objective To investigate the diagnostic value of Magnetic Dextran Enhanced Magnetic Resonance Angiography (Gd-DTPA-MRA) and related MRI changes in the diagnosis of moderate and severe herpes simplex virus encephalitis (HSE) and the therapeutic application of edaravone. Methods A retrospective analysis of 53 cases of moderate and severe HSE patients with cerebro-spinal fluid routine, electroencephalogram, brain CT examination, etc. were performed MRI and MRA examination, 48 cases were diagnosed, the patients were randomly divided into two groups, the experimental group according to Dalaman with the traditional antiviral therapy, the control group of 22 conventional antiviral therapy. Results MRA showed the whole cerebral arteries and fine branches and veins system, 48 cases of herpes simplex encephalitis enhanced magnetic resonance angiography showed normal. The clinical efficiency of the experimental group was significantly higher than the control group, there are differences (P <0.05). Conclusion The clinical application of enhanced MRA in patients with suspected HSE diagnosis, edaravone on the treatment of HSE has a significant effect.