【摘 要】
：
A classical function of Clq is to bind immune complexes and initiate complement activation producing membrane lytic complexes. opsonins and anaphylatoxins. This
【机 构】
：
Department of Microbiology,MRC Immunochemistry Unit
【基金项目】
：
the Singapore National Medical Research Council Grant
论文部分内容阅读
A classical function of Clq is to bind immune complexes and initiate complement activation producing membrane lytic complexes. opsonins and anaphylatoxins. This classical pathway of complement activation is also elicited when Clq binds some other ligands. Besides complement activation, Clq also regulates cell differentiation, adhesion, migration. activation and survival. Clq deficiency is associated with autoimmunity as well as increased susceptibility to infections. In this article. we discuss the basic properties of Clq, its expression, and classical and regulatory functions. Cellular & Molecular Immunology.2008;5(1):9-21.
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