论文部分内容阅读
近日,一项刊登在国际杂志Development上的研究报告中,来自约翰霍普金斯大学的研究人员通过研究利用细胞信号化合物的混合制剂成功逆转了人类胚胎干细胞(ESCs)的生物钟,从而就能赋予细胞相同的灵活性;研究者表示,促进干细胞的发育生物钟回归至早期阶段或许就能够为我们提供机会来诱导人类干细胞成为任何一种类型的细胞,从而用作器官移植和遗传性疾病模型的开发中,最终这些细胞或许就能够被用来开发出嵌合体动物。
In a recent study published in the International Journal of Development, researchers from Johns Hopkins successfully reversed the circadian clock of human embryonic stem cells (ESCs) by studying a cocktail of compounds that utilize cell signaling compounds Cells with the same flexibility; researchers say promoting the development of stem cells may return to the early stages of the developmental circadian clock, giving us the opportunity to induce human stem cells into any type of cell for use as a model for organ transplantation and genetic disease development In the end, these cells may eventually be used to develop chimeric animals.