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结直肠癌的根治性手术尽管已经切除了全部肉眼可见的病灶,但仍有1/5的Ⅰ、Ⅱ期结直肠癌患者将复发。通过免疫组化测得的淋巴微转移是光学显微镜下没有淋巴结侵犯的患者复发和发生癌症相关死亡的原因之一。然而淋巴微转移的生物学重要性仍未知。本研究目的是了解淋巴微转移对Ⅰ?
Radical surgery for colorectal cancer Although all macroscopic lesions have been excised, one in five patients with stage I and II colorectal cancer will relapse. Lymphatic micrometastasis by immunohistochemistry is one of the causes of recurrence and cancer-related death in patients undergoing a light microscopy without lymph node involvement. However, the biological importance of lymphatic micrometastases remains unknown. The purpose of this study is to understand the lymphatic micrometastasis Ⅰ?