肿瘤化疗常引起消化道反应,尤其顺氯氨铂(PDD)更为严重,几乎患者都有恶心、呕吐,约6%的病人因此拒绝用药而影响治疗。对化疗所致呕吐,近年来文献报道,皮质类固醇是预防PDD 所致呕吐最有效的药物。我们采用大剂量地塞米松和灭吐灵联合用药,取得了较好止吐效果。现报道如下。 Tumor chemotherapy often causes digestive tract reactions, especially cisplatin (PDD) is more serious, almost all patients have nausea, vomiting, and about 6% of patients therefore refused to use drugs and affect treatment. In response to chemotherapy-induced vomiting, corticosteroids have been reported in recent years as the most effective drug for preventing vomiting caused by PDD. We used a combination of high-dose dexamethasone and metoclopramide to achieve better antiemetic effects. The report is as follows.