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目的:探讨部分性脾栓塞(PSE)在肝癌介入治疗中的意义和方法。材料与方法:采用肝动脉化疗栓塞术(THAE)和PSE并用的方法治疗30例合并肝硬化、门脉高压和脾功能亢进的肝癌患者。将PSE的栓塞材料明胶海绵限制在160粒以内以防止过量栓塞。结果:27例脾栓塞面积在50%以上;25例脾功能亢进缓解;26例食管静脉曲张包括6例有消化道出血者,5例于PSE后1年之内未再发生出血;未发生脾脓肿等严重并发症。3例脾栓塞面积在50%以下的患者中2例脾功能亢进未缓解。结论:PSE与THAE并用是治疗肝癌合并肝硬化、门脉高压和脾功能亢进的安全、有效的方法。栓塞剂定量的方法有助于避免脾的过量栓塞,减少并发症。
Objective: To explore the significance and methods of partial splenic embolism (PSE) in interventional treatment of hepatocellular carcinoma. Materials and Methods: Thirty liver cancer patients with liver cirrhosis, portal hypertension and hypersplenism were treated with hepatic arterial chemoembolization (THAE) and PSE. The PSE embolic material gelatin sponge was limited to 160 to prevent excessive embolization. Results: Twenty-seven cases of splenic embolism were more than 50%; 25 cases of hypersplenism relieved; 26 cases of esophageal varices included 6 cases of gastrointestinal bleeding; 5 cases did not recur within 1 year after PSE; no spleen occurred. Abscesses and other serious complications. Of the 3 patients with splenic embolism less than 50%, 2 had no relief of hypersplenism. Conclusion: The combination of PSE and THAE is a safe and effective method for the treatment of liver cancer with liver cirrhosis, portal hypertension and hypersplenism. Quantitative embolization methods help to avoid excessive embolization of the spleen and reduce complications.