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细胞凋亡是细胞在生理和病理情况下的一种死亡模式,凋亡过程受基因严格调控。细胞凋亡是肝缺血—再灌注损伤重要的病理生理特征。本文对细胞凋亡、肝缺血—再灌注损伤中细胞凋亡的发生机制及凋亡相关基因的研究进展进行综述。
Apoptosis is a cell death pattern under physiological and pathological conditions. The process of apoptosis is strictly regulated by genes. Apoptosis is an important pathophysiologic feature of hepatic ischemia-reperfusion injury. This review summarizes the mechanism of cell apoptosis and apoptosis related genes in hepatic ischemia / reperfusion injury.