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1例70岁男性患者冠状动脉支架植入术后接受替格瑞洛(90 mg口服、2次/d)和阿司匹林肠溶片(100 mg口服、1次/d)双联抗血小板治疗.用药第2天患者发现痰中带少许血丝;此后数次出现唾液中带血丝;第42天突发大咯血,咯血量约100 ml.自行停用替格瑞洛.入院后给予吸氧、祛痰、止血等治疗,抗凝治疗调整为硫酸氢氯吡格雷(75 mg口服、1次/d)与阿司匹林肠溶片(剂量同前)联用.停用替格瑞洛第4天患者咯血量明显减少;第7天咯血停止.“,”A 70-year-old male patient received ticagrelor 90 mg twice daily and aspirin 100 mg once daily as dual antiplatelet therapy after operation for coronary stent implanting. On day 2 of treatment,he developed traces of blood in sputum. The hemoptysis became worse and times became more after that. On day 42,the patient developed massive hemoptysis about 100 ml. Ticagrelor was discontinued by himself. The patient then was given oxygen inhalation,expectorant drug and hemostatic agents. Anticoagulant therapy was adjusted for the combined use of clopidogrel 75 mg once daily and aspirin 100 mg once daily. On day 4 of the ticagrelor withdrawal,the amount of hemoptysis was obviously reduced. On day 7,the hemoptysis ceased.