在肺的血流调节支气管平滑肌的舒缩以及肺部炎症或变态反应等的发生机制中都有化学介质的参与。近年来认识到肺除了进行气体交换,它还是一个重要的化学介质的合成和代谢器官。所以探讨化学介质在肺内的合成、代谢和与肺部疾患的关系,将对肺部疾患的诊治有很大的帮助。由于肺是化学介质前列腺素生物合成、释放和灭话的主要场所,亦是人体中含前列腺素浓度很高的组织之一,前列腺素代谢异常与肺部疾患的关系逐渐引起重视。本文 Chemical mediators are involved in the mechanisms by which pulmonary blood flow modulates bronchial smooth muscle relaxation and contraction, as well as pulmonary inflammation or allergic reactions. In recent years, it has been recognized that in addition to gas exchange, the lungs are also an important synthesis and metabolic organ of chemical mediators. So to explore the synthesis of chemical mediators in the lungs, metabolism and the relationship between lung disease, lung disease diagnosis and treatment will be of great help. As the lungs are the main sites of biosynthesis, release and extinction of prostaglandins in the chemical medium, they are also one of the tissues with high concentrations of prostaglandins in the human body. The relationship between abnormalities of prostaglandins and lung diseases gradually attracts attention. This article