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采用吡喹酮500mg／kg总量于感染血吸虫尾蚴后21天和25天一次灌服早期治疗小白鼠血吸虫病，结果显示感染尾蚴后25天用药组效果明显优于21天用药组。提示吡喹酮早期治疗预防日本血吸虫病和控制急性血吸虫病服药时间应在接触疫水25天后为宜。
Using praziquantel 500mg / kg total amount of Schistosoma japonicum Schistosome infection 21 and 25 days after the early treatment of schistosomiasis in mice, the results showed that 25 days after infection with cercariae treatment group was significantly better than the 21-day treatment group. Tip praziquantel early treatment of schistosomiasis japonica prevention and control of acute schistosomiasis medication time should be exposed to 25 days after the water is appropriate.