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目的探讨妊娠期妇女外阴阴道假丝酵母菌病的临床治疗策略及效果。方法选择济源市人民医院门诊2012年1月至2013年1月收治的外阴阴道假丝酵母菌的妊娠期妇女86例,随机数字法分为两组,每组43例,对照组患者接受达克宁栓治疗,观察组患者在此基础上联合碳酸氢钠溶液擦洗阴道。并对两组患者的临床效果、并发症及复发情况进行比较。结果观察组患者治疗后总有效率达97.7%,显著高于对照组的79.1%(P<0.05),治疗后30 d两组复发率分别为2.3%和18.6%,观察组显著低于对照组(P<0.05),两组并发症率分别为4.7%和11.6%,差异无统计学意义(P>0.05),经治疗后均缓解。结论外阴阴道假丝酵母菌病是妊娠期妇女常见病,采用达克宁栓联合碳酸氢钠溶液擦洗阴道治疗可显著改善患者症状,效果显著,安全,复发率低,值得推广。
Objective To investigate the clinical strategy and effect of vulvovaginal candidiasis in pregnant women. Methods 86 pregnant women with genital Candida vulgaris admitted from January 2012 to January 2013 in Jiyuan People’s Hospital were randomly divided into two groups (43 cases in each group). The control group received metoclopramide Treatment, observation group patients on this basis combined with sodium bicarbonate solution scrub vagina. The clinical effects, complications and recurrence of the two groups were compared. Results The total effective rate of the observation group was 97.7% after treatment, significantly higher than 79.1% (P <0.05) of the control group. The recurrence rates of the two groups after treatment were 2.3% and 18.6% respectively, significantly lower than those in the control group (P <0.05). The complication rates of the two groups were 4.7% and 11.6%, respectively, with no significant difference (P> 0.05), and were relieved after treatment. Conclusions Vulvovaginal candidiasis is a common disease in women during pregnancy. Dacron suppository combined with sodium bicarbonate solution scrub vaginal therapy can significantly improve the symptoms of patients. The results are significant, safe and low recurrence rate, which deserves promotion.