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目的探讨CT灌注检查在乳腺癌和急、慢性乳腺炎症诊断中的应用价值。方法对术后病理证实为浸润型乳腺癌(18例)、急性乳腺炎症(11例)、慢性乳腺炎(8例)的CT灌注检查资料,采用GEAW4.1工作站perfusion3体部肿瘤灌注软件行图像后处理,得出各组病变的灌注参数,采用配对样本t检验与对侧正常乳腺组织的灌注参数进行比较,同时采用独立样本t检验对各组病变的灌注参数进行对照分析,以P<0.05作为差异具有统计学意义。结果乳腺癌及急性乳腺炎症的表面通透性(PS)、血容量(BV)、血流量(BF)均高于对侧正常乳腺组织(P<0.05)。急性乳腺炎症的PS、BV高于乳腺癌,而BF低于乳腺癌(P<0.05)。慢性乳腺炎的PS、BV、BF均低于乳腺癌(P<0.05),慢性乳腺炎的PS低于对侧正常乳腺组织(P>0.05)。结论 CT灌注检查可以反映乳腺病变的血流灌注特性,是诊断乳腺病变的可行的辅助检查方法,为诊断及鉴别诊断提供重要的影像学依据。
Objective To investigate the value of CT perfusion in the diagnosis of breast cancer and acute and chronic mastitis. Methods The postoperative pathology was confirmed by CT perfusion of infiltrative breast cancer (18 cases), acute mastitis (11 cases) and chronic mastitis (8 cases). The perfusion software of GEAW4.1 workstation After treatment, the parameters of perfusion in each group of lesions were obtained. The parameters of paired samples were compared with the perfusion parameters of the contralateral normal breast tissue. At the same time, the independent samples t test was used to compare the perfusion parameters of each group with P <0.05 As a difference with statistical significance. Results The surface permeability (PS), blood volume (BV) and blood flow (BF) of breast cancer and acute mastitis were all higher than those of normal breast (P <0.05). Acute mastitis PS, BV higher than breast cancer, and BF is lower than breast cancer (P <0.05). Chronic mastitis PS, BV, BF were lower than breast cancer (P <0.05), chronic mastitis PS lower than the contralateral normal breast tissue (P> 0.05). Conclusion CT perfusion examination can reflect the perfusion characteristics of breast lesions. It is a feasible method to diagnose breast lesions. It provides an important imaging evidence for diagnosis and differential diagnosis.