论文部分内容阅读
[目的]探讨术前炎性因子水平对行结直肠癌根治术患者预后情况的影响。[方法]82例行结直肠癌根治术的患者作为研究对象,对其术前炎性因子水平及预后情况进行回顾性研究,进行相关性分析。对有差异的因素进行Logistic多因素回归分析。[结果]病理分期及各项术前炎性因子水平均会对患者3年生存率产生影响,差异有统计学意义(P<0.05)。Logistic多因素回归分析结果显示,TNF-α、IL-6、IL-8表达水平以及GPS评分是影响患者预后的独立危险因素。[结论]术前炎性因子对于预测结直肠癌根治术后患者预后具有一定意义,应作为常规检测指标。
[Objective] To investigate the effect of preoperative inflammatory cytokines on the prognosis of patients with colorectal cancer undergoing radical operation. [Methods] 82 patients undergoing radical resection of colorectal cancer were studied, and their preoperative inflammatory cytokines levels and prognosis were retrospectively studied and their correlations were analyzed. Logistic regression analysis was used to analyze the differences. [Results] The pathological staging and preoperative inflammatory cytokines levels all had an impact on the 3-year survival rate of patients, the difference was statistically significant (P <0.05). Logistic regression analysis showed that the expression of TNF-α, IL-6 and IL-8 as well as GPS score were independent risk factors affecting the prognosis of patients. [Conclusion] The preoperative inflammatory factors have certain significance for predicting the prognosis of patients after radical operation of colorectal cancer, and should be used as routine test indicators.