本文报道了某工业企业1966～1972年接触环氧树脂中甲撑替二苯胺(methylenedianiline)的13名青工发生肝炎事件的回顾性调查。于患者病愈10周至5年半后,从医师处得到患者当时的病情记录,并对他们进行了访问和检查(一人未作)。此外,用随机抽样法对该厂从事同样工作而无肝炎病史者中抽取21名工人进行了同样的访问和检查。收集了有关甲撑替二苯胺(以下简称MDA)的接触条件和毒性资料,并由有关单位进行了动物毒性试验。13名患者为20～36岁的男子,他们皆无肝胆系疾患或变态反应病史,无饮用过量酒精或其他药物史,也无病毒性肝炎 This article reports the retrospective investigation of 13 young workers who had exposure to methyldiamine in an industrial enterprise from 1966 to 1972. Ten to five and a half years after the patient recovered, the patient’s medical history was obtained from the physician and interviewed and examined (none of them). In addition, a random sample of 21 workers from the same factory working without a history of hepatitis was interviewed and examined in the same manner. The contact conditions and toxicity data on methyl diphenylamine (hereinafter referred to as MDA) were collected and the animal toxicity test was carried out by the relevant units. Thirteen patients, 20 to 36 years old, had no history of hepatobiliary disease or allergy, no alcohol or other medication, and no viral hepatitis