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儿茶酚胺类是一类参与神经传达的生理活性物质,主要有去甲肾上腺素、肾上腺素、左旋多巴和多巴胺等四种物质。儿茶酚胺的分离和测定能为生物化学、药物学和临床医学提供重要信息,因此受到人们的关注。Kissinger等首先用高效液体色谱一电化学检测法进行了儿茶酚胺类的分离和测定,石井,后藤等应用微型高效液体色谱—电化学检测法的工作也取得了进展。上述方法避免了气体色谱法要形成挥发性衍生物或高效液体色谱—荧光检测法形
Catecholamines are a class of physiologically active substances that are involved in nerve transmission. They are mainly norepinephrine, epinephrine, levodopa and dopamine. Catecholamine separation and determination of biochemistry, pharmacology and clinical medicine to provide important information, so that people’s attention. Kissinger et al. First performed the separation and determination of catecholamines by high performance liquid chromatography-electrochemical detection. Progress has also been made in the use of Ishikawa, Goto et al. For the detection of catecholamines. The above method avoids the gas chromatography to form volatile derivatives or high performance liquid chromatography - fluorescence detection method