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目的 探讨支气管动脉灌注化疗药的并发症发生原因、处理原则及预防措施。方法 回顾性分析２１４例次支气管动脉灌注化疗病例中的较严重并发症１２例次（５． ６％）。结果 皮肤损害９例次（４．２％），脊髓损伤２例次（０．９％），股动脉血栓形成１例次（０．５％），经对症处理，以上并发症基本恢复。结论 并发症的发生与血管变异、造影剂及化疗药种类、浓度、推注速度有明显关系。轻柔熟练操作，辨清血管解剖，使用非离子型造影剂，低浓度、低毒性、慢速推注化疗药可预防或降低并发症的发生。
Objective To investigate the causes of complications of bronchial arterial infusion chemotherapy drugs, principles of treatment, and preventive measures. Methods A retrospective analysis of 214 cases of secondary bronchial arterial infusion chemotherapy in 12 cases (5.6%). Results There were 9 cases of skin lesions (4.2%), 2 cases of spinal cord injury (0.9%), and 1 case of femoral artery thrombosis (0.5%). After symptomatic treatment, the above complications basically recovered. Conclusion The occurrence of complications is closely related to the variation of blood vessels, the types and concentration of contrast agents and chemotherapeutics, and the injection rate. Gentle manipulation, identification of vascular anatomy, use of non-ionic contrast agents, low concentration, low toxicity, slow bolus injection of chemotherapy drugs can prevent or reduce the occurrence of complications.