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半个多世纪以来,人们对组胺在机体生理、病理过程中的作用进行了广泛的研究,肯定了它在全身性过敏反应、胃酸分泌及某些心律失常中的作用,为临床诊断和治疗提供了理论和方法。近年的许多研究发现,组胺与植物神经系统的作用有着广泛的联系,本文主要综述这方面研究的进展。组胺与植物神经系统相互作用的形态学基础体内组胺的贮存部位主要有两个:一是血液循环中的嗜碱性粒细胞,一是组织中的肥大细胞。肥大细胞质膜表面有M、α或β-受体。Neuson(1983)用电子显微镜观察到,豚鼠回肠隐窝神经-肥大细胞接触处存在有终扣,这些终扣与细胞器的结构不同,一些充满许多小而清晰的囊泡(Φ=40～50nm)和少量较大的囊泡(Φ=80～100nm)。
For more than half a century, the role of histamine in the physiological and pathological processes of the body has been extensively studied, affirming its role in generalized allergic reactions, gastric acid secretion and certain arrhythmias for the clinical diagnosis and treatment Provided the theory and method. In recent years, many studies have found that histamine and the role of the autonomic nervous system has a broad relationship, this paper reviews the progress of this research. Histamine and autonomic nervous system interaction based on the morphological basis of histamine storage site there are two main: First, blood circulation in basophils, one is the mast cells in the organization. Mast cell plasma membrane surface M, α or β-receptor. Neuson (1983) observed by electron microscopy that guinea pig ileal recess neuronal-mast cell contacts exist at the end of the deduction, the terminal structure with organelles different, some filled with many small and clear vesicles (Φ = 40 ~ 50nm) And a small number of larger vesicles (Φ = 80 ~ 100nm).