【摘 要】
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It has been proposed that some of CNS responses to peripheral immune challenge are activated by a neural route especially via afferent fibers in the vagal nerv
【出 处】
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Acta Pharmacologica Sinica
论文部分内容阅读
It has been proposed that some of CNS responses to peripheral immune challenge are activated by a neural route especially via afferent fibers in the vagal nerve.In the present study, the expression of early-immediate gene c-fos in rat brain following an intraperitoneal injection of lipopolysaccharides ( LPS, 20 μg·kg~(-1)) was observed and the effect of subdiaphragmatic vagotomy to the Fos expression as well as the existence of type Ⅰ of IL-1 receptor (IL-lRI) in nodose ganglion were examined by
It has been proposed that some of CNS responses to peripheral immune challenges are activated by a neural route particularly via afferent fibers in the vagal nerve. In the present study, the expression of early-immediate gene c-fos in rat brain following an intraperitoneal injection of lipopolysaccharides (LPS, 20 μg · kg -1) was observed and the effect of subdiaphragmatic vagotomy to the Fos expression as well as the existence of type Ⅰ of IL-1 receptor (IL-lRI) in nodose ganglion by
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