论文部分内容阅读
在室温条件下,以邻菲罗啉作为配体,无水氯化镍催化的Negishi偶联反应合成了一系列6位链状仲烷基取代的嘌呤化合物.该方法反应条件温和、原料易得、产物收率高.
A series of 6-chain secondary alkyl substituted purine compounds were synthesized by using Negishi coupling reaction catalyzed by anhydrous nickel chloride with phenanthroline as the ligand at room temperature.The reaction conditions are mild and the raw materials are easily available , High product yield.