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最近报道消炎痛可抑制肾脏前列腺素的合成,减少锂在肾脏的消除,从而增加血浆中锂的浓度。3个病人和4个健康受试者服用消炎痛(150mg/d)
Recently reported indomethacin can inhibit the synthesis of renal prostaglandin, reducing the elimination of lithium in the kidneys, thereby increasing the concentration of lithium in plasma. Three patients and four healthy subjects took indomethacin (150 mg / d)