恶性肿瘤患者往往伴有凝血机制障碍,血液处于“高凝状态”。前已报道赤芍合并化疗药物治疗肿瘤有明显增效作用。为探索其增效机理,本研究测定了S-180实体瘤小鼠和正常昆明鼠血浆纤维蛋白原含量和反映纤维蛋白溶解活性的优球蛋白溶解时间(ELT)。发现S-180实体瘤10天鼠血浆纤维蛋白含量比正常小 Patients with malignant tumors are often accompanied by clotting disorders and the blood is in a hypercoagulable state. It has been reported previously that red peony and chemotherapeutic drugs have significant synergistic effects on the treatment of tumors. In order to explore its synergistic mechanism, this study measured plasma fibrinogen content and eukaryotic lysis time (ELT) reflecting fibrinolytic activity in S-180 solid tumor mice and normal Kunming mice. Found that S-180 solid tumor 10 days rat plasma fibrin content than normal