用化学发光法观察到叔丁基氢过氧化物对培养的小鼠腹腔巨噬细胞呼吸爆发有强烈的抑制作用。云芝多糖经腹腔注射后,能增强巨噬细胞呼吸爆发功能对叔丁基氢过氧化物损伤的抵抗力。云芝多糖处理的巨噬细胞谷胱甘肽过氧化物酶基础活力显著提高,在叔丁基氢过氧化物作用下,云芝多糖处理的巨噬细胞仍有较高的谷胱甘肽过氧化物酶活力。说明巨噬细胞的免疫功能与谷胱甘肽过氧化物酶活力有关,非特异性免疫多糖可提高细胞抗氧化能力,减轻活性氧损伤作用。 Chemiluminescence was observed t-butyl hydroperoxide on cultured mouse peritoneal macrophage respiratory burst has a strong inhibitory effect. Coriolus versicolor polysaccharide after intraperitoneal injection, can enhance the respiratory burst function of macrophages on tert-butyl hydroperoxide damage resistance. The basic activity of glutathione peroxidase of macrophages treated with polysaccharides of Coriolus versicolor was significantly increased. Under the action of t-butyl hydroperoxide, macrophages treated with polysaccharides of Corundum still had higher glutathione peroxides Enzyme activity. The results showed that the immune function of macrophages was related to the activity of glutathione peroxidase. Non-specific immunopolysaccharide could improve the anti-oxidative capacity of cells and reduce the reactive oxygen species damage.