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目的通过对日军鼠疫细菌战9名F1抗体阳性幸存者的流行病学资料分析,为丽水历史上鼠疫暴发是由日军细菌战所引发提供证据。方法通过浙西南“侵华日军细菌战”档案抢救与保护中心寻访鼠疫细菌战受害幸存者并进行鼠疫F1抗体检测,对检测获得F1抗体阳性的幸存者从传染情况、医治情况、后遗症等方面进行流行病学回顾性调查分析。结果时隔70年检测到高滴度F1抗体的幸存者当年发病时均有与日军实施细菌战明显相关的流行病学史,且患病时均有高热和淋巴结肿大,留下不同程度的后遗症。结论 9名日军鼠疫细菌战幸存者体内F1抗体阳性,依据鼠疫有关诊断标准,日军鼠疫细菌战曾给丽水造成鼠疫的短期流行。
OBJECTIVE: To analyze the epidemiological data of nine F1-positive survivors of the Japanese plague bacteriosis in the history of war in Lishui. Methods Surveillance of Plague F1 antibodies was carried out by means of the Survival and Protection Center of Bacterial Warfare Invading China by Japanese Army in Zhejiang Province. The survivors who tested positive for F1 antibody were investigated from the aspects of infection, treatment, sequelae, etc. Epidemiological retrospective investigation and analysis. Results The survivors of high titer antibody of F1 antibody after seventy years had a history of epidemiology significantly related to the Japanese army’s bacteriological warfare at the time of onset of the disease and all had hyperpyrexia and lymphadenopathy when diseased, leaving varying degrees of Sequelae. Conclusion Nine Japanese plague bactericidal survivors were positive for F1 antibody in vivo. According to the diagnostic criteria of the plague, the plague of the Japanese plague gave Lishui a short-term epidemic.