The progress on the molecular design, synthesis and characterizations of some kinds of pyridine-containing heteroaromatic polymers in main chain were reviewed in this paper, they would include polyimides (PIs), polypyrrolones (PPYs), poly(pyrrolone-imide)s (PPIs), and poly(pyrrolone-benzimidazone)s (PPBs) containing pyridine moieties. The pyridine-containing polymers reported all exhibit good processability, excellent thermal properties and mechanical properties. However, the contribution of pyridine ring to polymers properties is still need to research further, the heteroaromatic polymers containing pyridine moieties have focused by more and more researchers. The progress on the molecular design, synthesis and characterizations of some kinds of pyridine-containing heteroaromatic polymers in main chain were reviewed in this paper, they would include polyimides (PIs), polypyrrolones (PPYs), poly (pyrrolone-imide) s The pyridine-containing polymers reported all exhibit good processability, excellent thermal properties and mechanical properties. However, the contribution of pyridine ring to polymer properties is still need to research further, the heteroaromatic polymers containing pyridine moieties have focused by more and more researchers.