探讨鼻腔手术后填塞纱条所引起的中毒性休克综合征患者的发病机理及临床特征。方法：对２例中毒性休克综合征患者的临床资料进行分析。结果：①本征为感染金葡菌产生的外毒素所致；②临床特征为持续高热、严重腹泻、低血压等急性中毒症状；③并发症多，死亡率高，病情轻重与细菌毒素释放量、毒力、种类及机体免疫反应有关。结论：鼻部手术后填塞物不宜放置过久，消毒要充分，一旦出现ＴＳＳ症状，应立即取出填塞物，及时采取治疗措施；治疗应给予足量有效的抗金葡菌抗生素。 To investigate the pathogenesis and clinical features of patients with toxic shock syndrome caused by packing gauze after nasal surgery. Methods: The clinical data of 2 patients with toxic shock syndrome were analyzed. Results: (1) The etiology was caused by exotoxin produced by Staphylococcus aureus; (2) The clinical features were persistent fever, severe diarrhea, hypotension and other acute poisoning symptoms; (3) high complication, high mortality, severity of illness and bacterial toxin release , Virulence, species and immune response. Conclusion: The stuffing should not be placed too long after nasal surgery, disinfection should be sufficient, once the symptoms of TSS, the stuffing should be removed immediately and take timely treatment; treatment should be given sufficient and effective anti-Staphylococcus aureus antibiotics.