A real-time path planning approach based on asynchronous double-precision windows is proposed for unmanned aerial vehicles (UAVs). In this proposed method, cursory paths and elaborate paths are planned respectively in the global and local windows. Specifically, global cursory path planner and local elaborate path planner are integrated by rolling two windows on different frequencies with different modes. Simulation results demonstrate that the proposed approach is effective for realizing a balance between the optimality and the time efficiency of online path planning by adapting the range of windows and the precision of samples. A real-time path planning approach based on asynchronous double-precision windows is proposed for unmanned aerial vehicles (UAVs). In this proposed method, cursory paths and elaborate paths are planned respectively in the global and local windows. Specifically, global cursory path planner and local elaborate path planner are integrated by rolling two windows on different frequencies with different modes. Simulation results demonstrate that the proposed approach is effective for realizing a balance between the optimality and the time efficiency of online path planning by adapting the range of windows and the precision of samples.