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通过B型超声波对3393例不同临床类型病毒性肝炎患者及543例对照组的观察,发现胆结石的发生率,肝病组明显高于对照组(P<0.001),而且对照组与急性肝炎组无差异(P>0.05),急性肝炎组低于慢性肝炎组(P<0.05),慢性肝炎组低于肝硬变组(P<0.001)。重型肝炎组胆结石发生率与急性肝炎组、慢性肝炎组及对照组比较无差异(P>0.05),但明显低于肝硬变组(P<0.001).胆结石的发生率有随年龄增长而升高的趋势,而肝病可使胆结石的发生趋向年轻化。研究结果提示:病毒性肝炎患者是胆结石的高发人群。而患者的年龄、病程长短及肝功能受损程度可影响病毒性肝炎合并胆结石的发生率。
The incidence of gallstones in 3393 patients with different clinical types of viral hepatitis and 543 controls by B-mode ultrasound was significantly higher in liver disease group than in control group (P <0.001), and there was no significant difference between control group and acute hepatitis group (P <0.05), but lower in acute hepatitis group than in chronic hepatitis group (P <0.05), lower in chronic hepatitis group than in cirrhosis group (P <0.001). The incidence of gallstone in severe hepatitis group was not significantly different from those in acute hepatitis group, chronic hepatitis group and control group (P> 0.05), but significantly lower than those in cirrhosis group (P <0.001). The incidence of gallstone was increased with age The rising trend, and liver disease can make the occurrence of gallstones tend to be younger. The results suggest that: patients with viral hepatitis is a high incidence of gallstone. The patient’s age, duration of disease and degree of impaired liver function can affect the incidence of viral hepatitis associated with gallstones.