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目的:探讨血脂正常老年高血压患者服用阿托伐他汀的血压变化情况及临床效果。方法:将110例血脂正常的老年高血压患者随机分为对照组和观察组,各55例,比较常规用药与加用阿托伐他汀治疗后的血压指标和血脂指标变化情况。结果:两组患者舒张压、收缩压和脉压等血压指标比较差异并不明显(P>0.05);与对照组相比,观察组总胆固醇降低较为明显(P<0.05)。结论:血脂正常高血压患者服用阿托伐他汀可发挥其协同降压作用,与降脂作用并无明显关联。
Objective: To investigate the changes of blood pressure and clinical effect of atorvastatin in elderly patients with essential hypertension with hypertension. Methods: A total of 110 elderly hypertensive patients with normal blood lipids were randomly divided into control group and observation group, with 55 cases in each group. The changes of blood pressure and blood lipid after routine treatment and atorvastatin treatment were compared. Results: There were no significant differences in diastolic blood pressure, systolic blood pressure and pulse pressure between the two groups (P> 0.05). Compared with the control group, the total cholesterol in the observation group was significantly decreased (P <0.05). CONCLUSION: Atorvastatin in patients with normal blood pressure can exert its synergistic antihypertensive effect, which is not significantly associated with the lipid-lowering effect.