近年来纳络酮(Naloxooe)已广泛用于临床。它的治疗作用很多。本文重点概述它在儿科临床的应用。10多年前发现中枢神经系统(CNS)有吗啡受体后,有人进一步提出CNS存在3种吗啡受体(μ、k、σ)。近年在心、肝、肾和小肠也发现这些受体。这些受体能与内源性吗啡样物质(如β-内啡肽等)紧密结合。机体应激时,下丘脑释放因子促使垂体前叶释放 Naloxooe has been widely used clinically in recent years. It has a lot of therapeutic effects. This article highlights its clinical application in pediatrics. More than 10 years after the discovery of a morphine receptor in the central nervous system (CNS), it was further suggested that there are three morphine receptors (μ, k, σ) in the CNS. In recent years, these receptors have also been found in heart, liver, kidney and small intestine. These receptors bind tightly to endogenous morphine-like substances (such as beta-endorphin, etc.). Body stress, hypothalamic release factor to promote the anterior pituitary release