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为了解小儿感染期手术前后肾上腺皮质功能的变化规律,作者对22例急性化脓感染患儿进行术前、术后血浆皮质醇的测定,并以17例非感染性疾病患儿作对照。感染组中以腹腔内和全身感染14例为Ⅰ组,局部软组织感染8例为Ⅱ组,对照组17例为Ⅲ组。测定结果:感染Ⅰ组术前皮质醇平均值明显高于Ⅱ组、Ⅲ组、而Ⅱ、Ⅲ组之间无明显差异;感染Ⅰ组术前、术后皮质醇均值相比亦有显著差异,感染Ⅱ组术前、术后皮醇均值相比无明显差异.由此表明,皮质醇的改变与感染范围和程度关系密切:当感染范围局限于体表软组
In order to understand the changing regularity of adrenocortical function before and after infection in children, 22 children with acute purulent infection were treated with preoperative and postoperative plasma cortisol, and 17 children with non-infectious diseases were used as controls. Among the infected groups, 14 cases were infected by intraperitoneal and systemic infection with group Ⅰ, 8 cases with local soft tissue infection as group Ⅱ, and 17 cases with control group as group Ⅲ. The results showed that the mean preoperative cortisol level in group Ⅰ was significantly higher than that in group Ⅱ and group Ⅲ, while there was no significant difference between group Ⅱ and group Ⅲ. The average preoperative and postoperative cortisol levels in group Ⅰ were significantly different, There was no significant difference between the two groups in preoperative and postoperative skin alcohol mean.It shows that the change of cortisol is closely related to the extent and extent of infection: when the infection range is limited to body surface soft tissue