一九六二年,Merrifield首先在苯乙烯和二乙烯基苯聚合物骨架上连结功能基制成聚合物试剂,并将后者用于肽的固相合成,从而为有机合成提供了一种新的合成方法,也找到了苯乙烯和二乙烯基苯共聚物的新用途.聚合物试剂是指具有一定性能的、在聚合物骨架上连结有以共价键相结合的功能基组分的一类反应性高分子物质.由于聚合物的交联度与其机械性能、溶解能力有密切关系,因 In 1962, Merrifield first used a functional group-based polymer reagent on the styrene and divinylbenzene polymer backbone and used the latter in the solid-phase synthesis of peptides to provide a new Of the synthetic methods, but also found a new use of styrene and divinylbenzene copolymer.Polymeric reagent refers to a certain performance, the polymer backbone linked to covalently bonded functional group component of a Reactive macromolecule material.As the degree of crosslinking of the polymer with its mechanical properties, solubility is closely related to