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自从大剂量氨基苄青霉素(以下简称氨苄)使用于临床以来,细菌性脑膜炎的治疗有了重大改观。本文报道了1967年至1974年间在法国某城市中心医院收治的205例8岁以下的细菌性脑膜炎,并对过去常规使用的三联疗法(即青霉素、氯霉素和磺胺甲基嘧啶)和单用氨苄疗法之间作了比较。对病原体的分析指出,脑膜炎球菌在本组病例中仍较突出,占38.5%(78例),其次肺炎球菌为9.7%(20例),流感杆菌为9%(19例),其他化脓菌为9%(19例),细菌未明的占33.5%(69例)。在其他化脓
Since the high-dose ampicillin (hereinafter referred to as ampicillin) used in clinical, the treatment of bacterial meningitis has made significant improvements. This article reports on 205 cases of bacterial meningitis under the age of 8 admitted to a city center hospital in France from 1967 to 1974 and analyzed the effects of conventional triple therapy (penicillin, chloramphenicol and sulfamerazine) and single A comparison between ampicillin therapy was made. Analysis of pathogens pointed out that meningococci were still prominent in this group of cases, accounting for 38.5% (78 cases), followed by pneumococcal 9.7% (20 cases), influenza bacilli 9% (19 cases), other pyogenic bacteria 9% (19 cases), the unexplained bacteria accounted for 33.5% (69 cases). In other purulent