【摘 要】
：
R-Enantiomer of the β-receptor antagonist N-[3-acetyl-4-(2-hydroxy-3-isopropylamino-propoxy)phenyl] butanamide with high enantioselectivity was synthesized fro
【出 处】
：
Science in China(Series B:Chemistry)
论文部分内容阅读
R-Enantiomer of the β-receptor antagonist N-[3-acetyl-4-(2-hydroxy-3-isopropylamino-propoxy)phenyl] butanamide with high enantioselectivity was synthesized from cheap starting materials and enantiopure chiral reagent through an efficient,convenient and practical synthetic strategy.Title product was detected by 1H NMR,13C NMR,and MS,and the enatiomeric excess was determined by chiral HPLC analysis using a chiracel AD-H column.
R-Enantiomer of the β-receptor antagonist N- [3-acetyl-4- (2-hydroxy-3-isopropylamino-propoxy) phenyl] butanamide with high enantioselectivity was synthesized from cheap starting materials and enantiopure chiral reagents through an efficient, convenient and practical synthetic strategy. The product was detected by 1H NMR, 13C NMR, and MS, and the enatiomeric excess was determined by chiral HPLC analysis using a chiracel AD-H column.
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