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目的探讨布地奈德治疗慢性阻塞性肺病急性加重期的临床疗效。方法选择我院2007年2月至2009年2月慢性阻塞性肺疾病急性加重期110例,随机分为两组,对照组和治疗组。在常规治疗的基础上,对照组雾化吸入硫酸沙丁胺醇,治疗组在对照组治疗基础上同时雾化吸入布地奈德。治疗7d后,比较肺功能的改善情况。结果治疗组治疗后与对照组治疗后肺功能比较,差异有统计学意义,P<0.01。结论在常规治疗基础上雾化吸入布地奈德治疗慢性阻塞性肺病,能够显著改善患者的肺功能,值得临床借鉴。
Objective To investigate the clinical efficacy of budesonide in the treatment of acute exacerbation of chronic obstructive pulmonary disease. Methods A total of 110 patients with acute exacerbation of COPD from February 2007 to February 2009 in our hospital were randomly divided into two groups: control group and treatment group. On the basis of routine treatment, the control group inhaled salbutamol sulphate inhalation, the treatment group inhaled budesonide inhalation on the basis of the control group. After 7 days of treatment, the improvement of lung function was compared. Results The lung function of the treatment group after treatment was significantly different from that of the control group after treatment (P <0.01). Conclusions The routine inhalation of budesonide in the treatment of chronic obstructive pulmonary disease can significantly improve the patient’s lung function, which is worthy of clinical reference.