本文报道1例(女婴,出生后体检发现腰骶部脊柱裂、脊膜膨出,双足马蹄内翻形。本例婴母无明显致畸原因,但其父却有明显长期服用氯丙嗪史,直至此次产前不久因服药过量而病故。因此,畸变原因推测可能与配偶在孕前长期服氯丙嗪导致精细胞畸 This article reported 1 case (female infant, post-birth physical examination found lumbosacral spina bifida, meningocele, bipedal horseshoe inside the case of infantile no significant teratogenic reasons, but his father had obviously long-term use of chlorpromazine Triazine history, until this prenatal soon died of overdose of medication, therefore, presumably because of distortion may be associated with the spouse before long-term exposure to chlorpromazine lead to sperm cell aberration