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目的 :探讨慢性低氧对大鼠肺血管左旋精氨酸 /一氧化氮 (L -Arg/NO)途径的影响。方法 :健康雄性SD大鼠 40只 ,体重 2 0 0~ 2 50g,随机分为对照 (C)组与低氧 (H)组 ,每组 2 0只。将低氧组大鼠置于常压低氧舱内 ,舱内充入氮气使氧浓度维持在 1 0 %± 0 5% ,CO2 浓
Objective: To investigate the effect of chronic hypoxia on the L-arginine / nitric oxide (L-Arg / NO) pathway in rat pulmonary arteries. Methods: Forty healthy male Sprague-Dawley rats weighing 200-250 g were randomly divided into control group (C) and hypoxia group (20). The hypoxia rats were placed in atmospheric hypoxia chamber filled with nitrogen so that the oxygen concentration maintained at 10% ± 0 5%, CO2 concentration