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目的:调查2012-2014年某部男性新兵血尿酸(UA)及谷丙转氨酶(ALT)升高情况。方法:2012-2014年某部男性新兵在我院复检共7960例,采用酶比色法检测血清UA和ALT水平,比较各年度血UA、ALT增高情况,以及UA和ALT同时增高情况,分析近3年来新兵患高尿酸血症和血ALT异常增高的趋势。结果:(1)2012年、2013年、2014年新兵复检血UA水平逐年增高,各年度比较差异显著(P<0.05);2013年高尿酸血症检出率显著高于2012年(P<0.05),2014年高尿酸血症检出率非常显著高于2012年和2013年(P<0.01)。(2)2012年和2013年血ALT水平差异不显著(P>0.05);2014年ALT水平显著高于2013年(P<0.05),非常显著高于2012年(P<0.01)。2014年ALT异常增高检出率显著或非常显著高于2012年和2013年(P<0.05,P<0.01)。(3)2012年、2013年、2014年同时检出高尿酸血症及ALT异常增高率分别为4.07%、4.42%和4.81%,各年度比较差异不显著(P>0.05)。结论:某部近3年来男性新兵复检高尿酸血症、ALT异常增高均呈逐年增高趋势,血UA、ALT同时异常增高检出率无显著增加。
Objective: To investigate the increase of serum uric acid (UA) and alanine aminotransferase (ALT) in a male recruits during 2012-2014. Methods: From 2012 to 2014, a total of 7960 male recruits in our hospital were recruited. The levels of serum UA and ALT were detected by enzymatic colorimetry. The levels of UA and ALT in blood and the increase of both UA and ALT were analyzed. Recruits in recent 3 years with hyperuricemia and blood ALT abnormal increase trend. Results: (1) The UA level of recruits in 2012, 2013 and 2014 was higher than that of 2012 (P <0.05). The detection rate of hyperuricemia in 2013 was significantly higher than that in 2012 (P < 0. 05). The detection rate of hyperuricemia in 2014 was significantly higher than that in 2012 and 2013 (P <0.01). (2) There was no significant difference in blood ALT levels between 2012 and 2013 (P> 0.05). ALT levels in 2014 were significantly higher than those in 2013 (P <0.05) and significantly higher than those in 2012 (P <0.01). The detection rate of abnormal ALT in 2014 was significantly or very significantly higher than that in 2012 and 2013 (P <0.05, P <0.01). (3) The rates of hyperuricemia and ALT abnormalities detected in 2012, 2013 and 2014 were 4.07%, 4.42% and 4.81% respectively, with no significant difference in each year (P> 0.05). Conclusion: In the recent 3 years, male recruits recheck hyperuricemia. The abnormal increase of ALT showed an increasing trend year by year. There was no significant increase in the simultaneous increase of blood UA and ALT.