胃肠黏膜不仅仅具有消化吸收的功能,还是人体一道重要的自然屏障。胃肠黏膜屏障功能障碍不仅见于胃肠道疾病、肝硬化、重症胰腺炎等消化科疾病,还经常继发于颅脑疾病、大面积烧伤、休克、严重感染、恶性肿瘤、放化疗等干预行为,需要引起内科、外科、神经科和儿科等多个科室临床医生的重视,是多学科共同研究的纽带。 Gastrointestinal mucosa not only has the function of digestion and absorption, but also an important natural barrier to human body. Gastrointestinal mucosal barrier dysfunction not only found in gastrointestinal diseases, cirrhosis, severe pancreatitis and other gastrointestinal diseases, often secondary to brain diseases, extensive burns, shock, severe infection, cancer, chemotherapy and other interventions , It needs to pay more attention to clinicians in many departments such as internal medicine, surgery, neurology and pediatrics, and it is a link of multidisciplinary research.