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目的:研究双黄连抑制甲1型流感病毒诱导细胞凋亡的机制。方法:将宫颈癌(Hela)细胞分成4组:病毒对照组、实验组、细胞对照组、药物对照组,采用流式细胞术计算细胞凋亡的百分率。结果:实验组细胞凋亡的百分率与病毒对照组比较有非常显著性差异(P<0.01)。结论:双黄连可抑制甲1型流感病毒诱导Hela细胞凋亡。
Objective: To study the mechanism of Shuanghuanglian in inhibiting the apoptosis induced by influenza A virus. Methods: The cervical cancer (Hela) cells were divided into 4 groups: viral control group, experimental group, cell control group, and drug control group. Flow cytometry was used to calculate the percentage of apoptosis. Results: The percentage of apoptosis in the experimental group was significantly different from the virus control group (P<0.01). Conclusion: Shuanghuanglian can inhibit Hela cell apoptosis induced by influenza A virus.