患者，男，47岁。因慢性咳嗽3+年，发现口腔溃疡伴疼痛1年入院。院外按腺周口疮治疗无效损疡疼痛加重，面积增大，数目增多（原来仅下颌前庭为一处，后逐渐又在下颌内侧面增多两处）。体查：T36．5℃，慢性病容，全身浅表淋巴结未扪及肿大。下唇肿胀，下颌前庭沟可见约4cm×0． Patient, male, 47 years old. Due to chronic cough 3 + years, found oral ulcer with pain 1 year admission. Hospital outside the treatment of gland weeks mouth sore invalid lesions increased pain, an increase in area, the number increased (the original only the mandibular vestibule for a, and gradually increased in the medial mandibular two). Physical examination: T36.5 ℃, chronic disease, systemic superficial lymph nodes without palpable enlargement. Lower lip swelling, mandibular vestibular groove can be seen about 4cm × 0.