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目的分析腹腔神经丛毁损术(NCPB)治疗癌性腹痛的疗效。方法 14例癌性腹痛患者在CT引导下行NCPB,评估术后1、4、8和12周的VAS疼痛评分,统计吗啡口服剂量和生存期,评估生活质量,记录术后并发症。结果术后12周内的VAS疼痛评分均比术前降低(P<0.01)。术后8周内,吗啡日口服量少于治疗前(P<0.01),生活质量提高(P<0.01)。14例患者术后生存36-195(105±47)d。术后96h内背部穿刺点疼痛12例,严重低血压3例,恶心呕吐2例,大汗伴有剧烈寒战1例;无其他明显远期并发症。结论 CT引导下实施NCPB,安全可靠,能有效缓解癌性腹痛,提高生活质量。
Objective To analyze the efficacy of celiac plexus ablation (NCPB) in the treatment of cancerous abdominal pain. Methods Fourteen patients with cancerous abdominal pain underwent CT-guided NCPB. VAS pain scores at 1, 4, 8 and 12 weeks after surgery were assessed. Oral doses and survival of morphine were assessed. Quality of life was assessed and postoperative complications were recorded. Results VAS pain score within 12 weeks after operation was lower than that before operation (P <0.01). Within 8 weeks after operation, morphine daily oral intake was less than before treatment (P <0.01), and quality of life improved (P <0.01). Fourteen patients survived 36-195 (105 ± 47) days postoperatively. In 96 hours after operation, there were 12 cases of back puncture pain, 3 cases of severe hypotension, 2 cases of nausea and vomiting, 1 case of hyperhidrosis with severe chills, and no other obvious long-term complications. Conclusion The implementation of CT guided NCPB, safe and reliable, can effectively relieve cancer of abdominal pain and improve quality of life.