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目的:探讨中西医结合治疗支气管哮喘缓解期患者免疫功能的变化。方法:将38 例患者随机分为2 组,治疗组20 例和对照组18 例。2 组均口服酮替芬1 m g/d,连用3 个月,肌注丙种球蛋白,每半个月肌注1 支(10% ,每支3 m l),应用3 个月。治疗组在此基础上口服“哮喘固本方”,每日1 剂,连服3 个月。2 组患者均连续观察3 年。结果:临床疗效治疗组总有效率100.0% ,明显优于对照组66.7% (P< 0.01)。治疗组治疗后IgG、IgA、IgM 明显升高,与治疗前比较均有显著性差异(P< 0.05 和P< 0.01),与对照组治疗后比较也均有显著性差异(P< 0.05 和P< 0.01)。结论:支气管哮喘缓解期患者在西药治疗基础上,加用中药“哮喘固本方”治疗可提高患者免疫力,增强疗效
Objective: To explore the changes of immune function in patients with remission of bronchial asthma treated with integrated traditional Chinese and western medicine. Methods: 38 patients were randomly divided into two groups, the treatment group of 20 patients and the control group of 18 patients. Both groups were given ketotifen 1 m g / d for 3 months, intramuscular gamma globulin, intramuscular injection every half month (10%, each 3 m l) for 3 months. On the basis of the treatment group, the treatment group orally “asthma Guben side” one day a day, and even for 3 months. Two groups of patients were observed for 3 years. Results: The total effective rate of the clinical curative effect group was 100.0%, which was significantly better than that of the control group (66.7%, P <0.01). After treatment, the levels of IgG, IgA and IgM in the treatment group were significantly higher than those before treatment (P <0.05 and P <0.01), and were significantly different from those in the control group after treatment (P <0.05 and P <0.01). Conclusion: Patients with bronchial asthma remission based on Western medicine treatment, plus traditional Chinese medicine “Asthma Gubenfang” treatment can improve patient immunity and enhance efficacy