消炎汤、保留灌肠联合西药治疗慢性结肠炎随机平行对照研究

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[目的]观察消炎汤、保留灌肠联合西药治疗慢性结肠炎疗效。[方法]使用随机平行对照方法,将80例住院患者按病志号抽签法简单随机分为两组。对照组40例柳氮磺胺吡啶片,1g/次,3次/d,无不适可增至4~6g/d,肠症缓解后可减至维持量1.5~2g/d。治疗组40例消炎汤(败酱草20g,白术、白芍、党参、甘草炙、黄芪、白花蛇舌草、乌梅、灵芝各15g,黄芩、广木香、软柴胡各9g,山慈菇6g;泄泻多次或黎明前泄加肉豆蔻、补骨脂、诃子各9g;脓血便加黄柏、白头翁各9g),1剂/d,水煎300m L,三次温服。保留灌肠(夏枯草、百及、三七各15g,蒲黄、黄连各5g),便后左侧卧位,臀部垫高10cm,导管插入肛门约20cm处,药液温度与体温相近,保留灌肠,30min/次,1次/d;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、便常规、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组痊愈22例,有效15例,无效3例,总有效率92.50%。对照组痊愈16例,有效14例,无效10例,总有效率75.00%。治疗组疗效优于对照组(P<0.05)。[结论]消炎汤、保留灌肠联合西药治疗慢性结肠炎疗效满意,无严重不良反应,值得推广。 [Objective] To observe the anti-inflammatory soup, retention enema combined with western medicine in the treatment of chronic colitis. [Methods] Using randomized parallel control method, 80 inpatients were randomly divided into two groups according to the random number of patients by lottery. Control group, 40 cases of sulfasalazine tablets, 1g / times, 3 times / d, no discomfort can be increased to 4 ~ 6g / d, relieve bowel disease can be reduced to maintain the amount of 1.5 ~ 2g / d. The treatment group of 40 cases of anti-inflammatory soup (Patrinia 20g, Atractylodes, Radix Codonopsis, licorice Sunburn, Astragalus, Hedyotis diffusa, ebony, Ganoderma lucidum 15g, skullcap, broad-wood, soft Bupleurum 9g, 6g; diarrhea or pre-dawn venting nutmeg, psoralen, myrobalan 9g; pus and blood will add cork, Pulsatilla 9g), 1 / d, decoction 300m L, three times warm clothes. Retention enema (Prunella, one hundred and thirty-seven each 15g, Puhuang, Coptis each 5g), then the left lateral position, hip pad 10cm, the catheter inserted into the anus about 20cm, liquid temperature and body temperature similar retention enema , 30min / time, 1 time / d; Western medicine treatment with the control group. Continuous treatment 14d for a course of treatment. Observed clinical symptoms, routine, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Result] In the treatment group, 22 cases were cured, 15 cases were effective and 3 cases were ineffective. The total effective rate was 92.50%. The control group cured 16 cases, effective in 14 cases, ineffective in 10 cases, the total effective rate was 75.00%. The treatment group was better than the control group (P <0.05). [Conclusion] The anti-inflammatory decoction and enema with western medicine in the treatment of chronic colitis have satisfactory curative effect and no serious adverse reactions, which deserves promotion.
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