热应激蛋白(HSP)是一组有核细胞内高度保守的由热应激基因编码的产物。其中以热应激蛋白70(HSP70)家族最为突出,该家族在正常细胞中含量较低,当机体受到外界化学或物理刺激时,其合成量反而增加。本文就HSP70表达与重金属、杀虫剂、二硫化碳、多环芳烃、磁场、职业噪声及激光等环境有害因素的关系进行综述,为环境有害因素的监测及暴露人群的保护提供依据。 Heat stress proteins (HSPs) are a group of highly conserved products encoded by heat-stressed genes in nucleated cells. Among them, the heat stress protein 70 (HSP70) family is the most prominent, the family of lower levels in normal cells, when the body by the outside world chemical or physical stimulation, the synthesis increased. This review summarizes the relationship between HSP70 expression and environmental factors such as heavy metals, insecticides, carbon disulfide, PAHs, magnetic fields, occupational noise and lasers, and provides evidences for the monitoring of environmental harmful factors and the protection of exposed populations.