论文部分内容阅读
【目的】比较单纯生活方式和加用二甲双胍对肥胖儿童血糖血脂相关指标治疗效果【方法】肥胖儿童101例根据OGTT分为组1,糖代谢正常高胰岛素血症组50例,组2,糖代谢异常组51例。组1A单纯生活方式治疗,组1B和组2二甲双胍加生活方式干预治疗1年。【结果】组1A治疗前后的体重指数,糖代谢指数,血脂,没有明显的改善(P>0.05)。组1B及组2治疗前后的体重指数,糖代谢指数,血脂,有明显的改善(P<0.01)。【结论】二甲双胍加用生活方式的干预优于单纯生活方式的干预。
【OBJECTIVE】 To compare the therapeutic effect of simple lifestyle and metformin on obesity in children with hyperlipidemia.Methods 101 obese children were divided into group 1 according to OGTT, 50 patients with normal glucose hyperinsulinemia, group 2, glucose metabolism Abnormal group of 51 cases. Group 1A simple lifestyle treatment, group 1B and group 2 metformin plus lifestyle intervention for 1 year. 【Results】 There was no significant improvement in body mass index, glycometabolic index and lipids before and after treatment in group 1A (P> 0.05). The body mass index, glycometabolism index and blood lipid of Group 1B and Group 2 before and after treatment were significantly improved (P <0.01). 【Conclusion】 Metformin plus lifestyle intervention is superior to simple lifestyle intervention.