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近年美国神经科第一位疾病由中风渐为痴呆所取代。研究表明,多发梗塞性痴呆与动脉硬化性皮层下脑病是脑动脉性痴呆的确切病因。一、多发梗塞性痴呆本病约占各种器质性痴呆的15~20%,高龄组可与 Alzheimer 氏病并存。欧美后者较多(占50%),前者占18%,二者合并占8%。日本前者占18.4%,后者占74%,二者合并占6.9%。(一)病理:Hachinski 等分析1313例老人尸检发现,无脑梗塞组痴呆占13%,1~4个梗塞灶组占26.9%,5~7个梗塞灶组占29.9%,8个以上梗塞灶组占36.4%。中等以上致命性大面积梗塞组占12.7%。结果证实多发性小梗塞灶对痴呆的发生起着
In recent years, the first neurological disease in the United States is gradually replaced by stroke. Studies have shown that multi-infarct dementia and atherosclerotic encephalopathy is the exact cause of cerebral artery dementia. First, the multi-infarct dementia The disease accounts for about 15 ~ 20% of various organic dementia, elderly group can coexist with Alzheimer’s disease. The latter Europe and the United States more (50%), the former accounted for 18%, the two combined accounted for 8%. Japan, the former accounted for 18.4%, the latter accounted for 74%, both combined accounted for 6.9%. (1) Pathology: Hachinski et al. (2005) found that 1313 cases of dementia in the elderly were found to have 13% dementia without cerebral infarction, 26.9% with 1 ~ 4 infarction, 29.9% with 5 ~ 7 infarction and 8 with infarction Group accounted for 36.4%. Middle-above fatal large infarction group accounted for 12.7%. Results confirmed that multiple small infarction on the incidence of dementia