感染细粒棘球蚴病的小白鼠经直茎紫堇总碱治疗后,其体内棘球蚴生发膜的超微结构有明显变化,主要表现为生发膜皮层细胞微毛消失,细胞器排列紊乱,胞浆中微管局限性扩张、破裂,溶酶体增多,高尔基复合体数目减少,线粒体肿胀和退行性变。棘球蚴生发膜外表面和内表面出现许多陷窝,如同“溃疡”外观。初步结果表明直茎紫堇总碱对细粒棘球蚴有广泛的细胞内效应。 In mice infected with echinococcosis, the ultrastructure of echinocyte hairpins in the echinocandins was significantly changed after treatment with the alkaloids of the stem stem purpura. The main manifestations were the disappearance of hairs and disordered organelles in the hair cells of the hair follicles. In the cytoplasm, the local microtubules expand and rupture, the lysosomes increase, the number of Golgi complexes decreases, and the mitochondrion swells and degenerates. Many lacunae appear on the outer surface and inner surface of the hydatid hairpin, like an “ulcer” appearance. Preliminary results indicate that the total alkaloids of C. purpura have a wide range of intracellular effects on Echinococcus granulosus.