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自1988年至1991年共收治25例先天性输精管缺如患者,在20例行手术诊治术中15例用自体睾丸精索鞘膜制成人工精池囊,5例又在囊内放置用微涤纶制成的异质管。术中抽吸10例附睾内精子进行快速活化,其中5例活化成功,行人工授精,结果2例怀孕,1例已生育一女孩。认为该症是有生育可能的,但需要解决3个问题:(1)采用显微外科技术把附睾内部活着的精子取出一定数量;(2)选配好快速活化剂使精子快速活化成功;(3)用患者的精浆培养自己的精子。建议对梗阻性无精子症在用手术疏通精路的同时可以采用快速活化精子技术行人工授精,以提高生育的效果。
From 1988 to 1991, a total of 25 patients with congenital absence of vas deferens were enrolled. Fifteen patients underwent surgical operation and surgical treatment with artificial spermatic cord from artificial spermatic cord sheath, and 5 were placed in the capsule Dacron made of heterogeneous tube. Intraoperative aspiration of 10 cases of epididymal sperm for rapid activation, of which 5 cases of activation was successful, artificial insemination, the results of 2 cases of pregnancy, 1 case of a child has been born. Think that the disease is fertile, but need to solve three problems: (1) the use of microsurgical techniques to remove a certain number of sperm inside the epididymis alive; (2) a good selection of fast activator sperm rapid activation success; ( 3) Cultivate your own sperm with the patient’s seminal plasma. Proposed obstructive azoospermia surgery to clear the sperm pathways can be used simultaneously with rapid activation of sperm technology artificial insemination to enhance the reproductive effects.