一、菌苗剂量和接种途径: 霍乱菌苗一般用皮下或肌肉注射两次(8×10~9个弧菌/毫升)间隔一到四周。十岁以下儿童减量(0.3～0.5毫升)。Verwey等(1969)发现注射两个剂量虽只间隔一周比一次能得到更高和持久的杀弧菌抗体,几乎一切受一次注射者都有显著和相当迅速的免疫反应。这些发现为在紧急情况下对成人使用一次注射提供血清学的合理性。也发现 First, the vaccine dose and route of vaccination: cholera vaccine is usually injected subcutaneously or intramuscularly twice (8 × 10 ~ 9 Vibrio / ml) interval of one to four weeks. Decrement of children under the age of 10 (0.3 ~ 0.5 ml). Verwey et al. (1969) found that injections of both doses resulted in higher and longer-lasting anti-Vibrio antibodies at intervals of one week, and almost all had a significant and fairly rapid immune response to one injection. These findings provide serological justification for using an injection for an adult in an emergency. Also found